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Applied mathematics is a branch of mathematics that concerns itself with the mathematical techniques typically used in the application of mathematical knowledge to other domains.

Historically, applied mathematics consisted principally of applied analysis, most notably differential equations, approximation theory (broadly construed, to include representations, asymptotic methods, variational methods, and numerical analysis), and applied probability. These areas of mathematics were intimately tied to the development of Newtonian Physics, and in fact the distinction between mathematicians and physicists was not sharply drawn before the mid-19th century. This history left a legacy as well; until the early 20th century subjects such as classical mechanics were often taught in applied mathematics departments at American universities rather than in physics departments, and fluid mechanics may still be taught in applied mathematics departments.

Today, the term applied mathematics is used in a broader sense. It includes the classical areas above, as well as other areas that have become increasingly important in applications. Even fields such as number theory that are part of pure mathematics are now important in applications (such as cryptology), though they are not generally considered to be part of the field of applied mathematics per se. Sometimes the term applicable mathematics is used to distinguish between the traditional field of applied mathematics and the many more areas of mathematics that are applicable to real-world problems.

Mathematicians distinguish between applied mathematics, which is concerned with mathematical methods, and applications of mathematics within science and engineering. A biologist using a population model and applying known mathematics would not be doing applied mathematics, but rather using it. However, nonmathematicians do not usually draw this distinction.

Historically, mathematics was most important in the natural sciences and engineering. However, in recent years, fields outside of the physical sciences have spawned the creation of new areas of mathematics, such as game theory, which grew out of economic considerations, or neural networks, which arose out of the study of the brain in neuroscience, or bioinformatics, from the importance of analyzing large data sets in biology.

The advent of the computer has created new applications, both in studying and using the new computer technology itself (computer science, which uses combinatorics, formal logic, and lattice theory), as well as using computers to study problems arising in other areas of science (computational science), and of course studying the mathematics of computation (numerical analysis). Statistics is probably the most widespread application of mathematics in the social sciences, but other areas of math are proving increasingly useful in these disciplines, especially in economics and management science.

Academic institutions are not consistent in the way they group and label courses, programs, and degrees in applied mathematics. At some schools, there is a single mathematics department, whereas others have separate departments for Applied Mathematics and (Pure) Mathematics. It is very common for Statistics departments to be separate at schools with graduate programs, but many undergraduate-only institutions include statistics under the mathematics department.